Ca2 channel antagonist

カタログ番号	製品名	別名	ターゲット
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T23301	(S)-(+)-Niguldipine hydrochloride		Others
	(S)-(+)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.		Others
T77710	Calcium Channel antagonist 2	WAY-327363	Calcium Channel
	Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.		Calcium Channel
T16897	SM-6586		Na+/Ca2+ Exchanger , Sodium Channel
	SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular disease and hypertension, among other diseases.		Na+/Ca2+ Exchanger , Sodium Channel
T8674	SR33805		Calcium Channel
	SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)		Calcium Channel
T13219	TTA-Q6		Calcium Channel
	TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cell...		Calcium Channel
T23391	SR 33805 oxalate		Others
	Ca2+ channel antagonist		Others
T28668	SB 201823-A	SB201823A,SB-201823-A
	SB 201823-A is a Ca2+ channel antagonist.
T30918	CI 951	CI-951,CI951
	CI 951 is a novel dihydronaphthyl Ca2+ antagonist and channel blocker.
T28489	R-(-)-Niguldipine hydrochloride
	R-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channel; alpha1A-adrenoceptor antagonist; antihypertensive agent; Less active enantiomer.
T28572	Ro 23-7014	Ro-23-7014
	Ro 23-7014, a new thiazepinone Ca2+ channel antagonist, has high affinity for peripheral (Type A) receptors.
T23225	(R)-(-)-Niguldipine hydrochloride		Others
	(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.		Others
T28172	Niguldipine hydrochloride	BY-935,Niguldipine HCl,B-85935,B-8509-035,B-859-35
	Niguldipine is a calcium channel antagonist. Niguldipine shows high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors.
T26970	CD-349	CD 349,CD349
	CD-349 is a calcium channel antagonist. CD-349 inhibits the noradrenaline (NA)-induced contraction of aortas in Ca2(+)-free medium.
T13220	TTA-Q6(isomer)		Others
	TTA-Q6(isomer) is an isomer of TTA-Q6. TTA-Q6 is a selective antagonist of the T-type Ca2+ channel.		Others
T70036	AJG-049 HCl
	AJG-049 HCl is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).
T71406	SA 2572
	SA 2572 is a newly synthesized Ca2+ antagonist having a inhibitory effect on the fast Na+ inward channel.
T70037	AJG-049 free base
	AJG-049 free base is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).
T12880	Semotiadil recemate fumarate		Calcium Channel
			Calcium Channel
T70682	AJ-3941
	AJ-3941 is a cerebrovascular-selective Ca2+ channel antagonist with anti-lipid peroxidative action. AJ-3941 may be useful in the treatment of cerebrovascular disorders.
T36808	UK 59811 hydrochloride
	Blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM). Tang et al (2016) Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagon...
TP1909	CALP2
	Cell-permeable calmodulin (CaM) antagonist that binds to the EF-hand/Ca2+-binding site. CALP2 has been demonstrated to inhibit CaM-dependant phosphodiesterase activity and increase intracellular Ca2+ concentrations by mo...
T62243	Bepridil hydrochloride hydrate
	Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a long-acting, non-selective antagonist of the calcium channel (Ca+channel), Bepridil hydrochloride hydrate is an inhibitor of the Na+,K+channel and ...
T33673	Niludipine	Niludipina,BAY-a 7168,Bay a 7168,Niludipinum
	Nirudipine is a double (2-propoxyethyl) analogist of nifedipine and a calcium channel blocker, which is also a safe anti-angina Ca2+ antagonist with a broad range of efficacy for all types of angina. At the same time, Ni...